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C., Lee, M
This effect was independent of IGF-1, a downstream mediator of GH-induced somatic growth, as IGF-1 treatment had minimal impact on the bone and BMAT changes (176, 337)
Interestingly, mediation analysis showed that TMAOs adverse effect on kidney function strengthened at more severe stages of cardiometabolic disease, implying TMAO synergy with existing pathology (thereby providing 2-hit model)
2025 Jan 9
A 2-year follow-up of the patients revealed an improvement in muscle strength, showing a potential activation of muscle regeneration
