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Reddy, P

This interaction initiates the transcription of a broad array of cytoprotective genes, markedly enhancing the synthesis of intracellular glutathione and upregulating phase II detoxification and antioxidant enzymes, including glutathione S-transferases (GSTs) and heme oxygenase-1 (HO-1)

However, it should be noted that there remains a dearth of large-scale randomized controlled trials investigating the potential role of vitamin D supplementation in improving IPF outcomes

A review indicates that specific microbial signatures can predict the efficacy of immune checkpoint inhibitors (ICI) (Verhaert and Aspeslagh, 2024)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Nordio M., Pajalich R