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New England Journal of Medicine Jastreboff AM, et al

Example 1 MDM Rationale: All three elements reached the high level in Example 1

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Notably, all patients had previously been treated with pentosan polysulfate, which is currently the only FDA approved treatment for interstitial cystitis, and had not responded

Follow the devices instructions when provided, which includes turning the dial to the proper dosage

Started with 0.25 mg subcutaneous injections each morning