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Sanguinarine reduces the expression of GPX4 and increases the expression of ACSL4, thereby inducing the ferroptosis of RCC cells (181)

Fan J, Char D, Bagby GJ, Gelato MC, Lang CH

Moreover, THC can diminish inflammation by impeding the activation of the JAK/STAT, Nrf2/HO-1, and JNK/ERK signaling pathways [50,51,52]
Research indicates that apigenin enhances the effectiveness of formulations by improving transdermal permeability and providing anti-inflammatory benefits [101]

Results are presented as mean values SEM

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