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Shim et al., 2019), as well as proinflammatory actions in mononuclear cells, enhancing adipocyte cytokine production (Purwar and Nagpure, 2022)

doi: 10.1097/ACI.0b013e32832d565c 21 AdamJPichlerWJYerlyD

Authors' Contributions AM: conceptualization, methodology, writing

Adiponectin, the most abundant adipokine in circulation [220], exerts its biological effects via two primary receptors (AdipoR1 and AdipoR2) [221], these receptors exhibit differential expression patterns across hepatic cell populations, including hepatocytes, HSCs, and KCs, mediating beneficial effects such as anti-inflammatory responses and anti-fibrotic actions [222, 223]

Chen Y, Yuan T, Zhang H, et al

Toxicol Lett 220(2):143149