glutathione peroxidase amino acids The interplay between 4 (GPX4), pyruvate kinase Frontiers | Research progress of

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In laboratory research models, GSH exerts its antioxidant activity through direct scavenging of reactive oxygen species (ROS) and reactive nitrogen species (RNS), as well as through serving as an essential cofactor for glutathione peroxidase (GPx) enzymes, which catalyse the reduction of hydrogen peroxide and lipid hydroperoxides to non-toxic products

Two other groups received HF diet for 12months accompanied by NAC for 12months (HFD+NAC(112)) or 6months (HFD+NAC(16))

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