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Circulating mitochondrial DNA in patients in the ICU as a marker of mortality: derivation and validation

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In contrast, our study confirmed decreased glutathione levels and increased ROS levels through BSO treatment or GCLC silencing, and revealed that while the depletion of glutathione did not compromise lymphoma cell survival in 2D culture, it sharply diminished viability in 3D gels

Upon consideration of both fluorescent staining results and Tali analyses, we concluded that this caspase-8 activation was not directly related to the apoptosis pathway, but instead was associated with the necrotic death pathway, particularly through the TNF-/caspase-8 axis

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