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In addition, it may be necessary to consider two pharmacodynamic variables: maximum effect attainable in the target tissue and the sensitivity of the tissue to the drug
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Consistent ncRNA fingerprints in readily obtainable specimens seminal plasma, follicular fluid, endometrial secretions, and circulating extracellular vesicles provide a foundation for minimally invasive diagnostics and real-time surveillance of reproductive health

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[DOI] [PMC free article] [PubMed] [Google Scholar] Dmitrieva VG, Torshina EV, Yuzhakov VV, Povarova OV, Skvortsova VI, Limborska SA, Dergunova LV

For instance, in the presence of TiO 2 NPs, NADPH oxidase was hyper-activated, and the subsequent increase in ROS generation induced a higher level of oxidative stress (Masoud et al., 2015)