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In conclusion, NAC use to improve renal outcomes in general surgery may be limited to instances of contrast-induced nephropathy, with minimal evidence for renal benefit in non-contrast surgeries

Total extract of Yupingfeng attenuates bleomycin-induced pulmonary fibrosis in rats

BPA induces ferroptosis of renal tubular epithelial cells in the kidney by promoting ferritinophagy through the activation of the AMPK-mTOR-ULK1 pathway

Cancers (Basel) 13 (22), 5625 (2021) J.D

Since this pathway use NADPH as electron donor, this compromises the availability of this coenzyme to regenerate reduced glutathione, exacerbating the oxidative stress [189]

Nature 435: 828833 Dews M, Homayouni A, Yu D, Murphy D, Sevignani C, Wentzel E, Furth EE, Lee WM, Enders GH, Mendell JT et al (2006) Augmentation of tumor angiogenesis by a Mycactivated microRNA cluster