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In the MMR-D group (20% of the overall population), the 12-month PFS was 67.9%, HR 0.42 (95% CI 0.220.80), for the durvalumab arm, and the 12-month PFS was 70%, HR 0.41 (95% CI 0.210.75), for the durvalumab and olaparib arm compared to 43.3% in the control arm (Table 1)

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11 Biochemical Pharmacology (PubMed)Glutathione in hepatic detoxification and conjugation

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Bhatt K, Bhagavathula M, Verma S, Timmins GS, Deretic VP, Ellner JJ, Salgame P