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The most pronounced changes were observed in the expression of -glutamate-cysteine ligase ( gshA ) and isocitrate dehydrogenase (icdA), which were upregulated by approximately 2-fold

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This will not only improve our understanding of ferroptosis and GIME but also provide a new solution for glioma immunotherapy resistance, a new breakthrough point for glioma treatment

The production of BSP libraries, sequencing, and bioinformatics analysis were performed as described in 18 with minor modifications

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Kheder E, Huang HJ, Wu A, Hong DS, Piha-Paul SA, Karp DD, Fu S, Subbiah V, Tsimberidou AM, Naing A, Diab A, Javle M, Kopetz S , Sood AK, Kurie JM, Meric-Bernstam F, Gleeson M, Janku F