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The cytotoxicity of 4-MESC was assessed by an MTT assay on RAW 264.7 cell lines

In the pipecolate pathway, lysine is converted into acetyl-CoA or pyruvate
doi: 10.3390/nu12113379 [DOI] [PMC free article] [PubMed] [Google Scholar] 33

RA is characterized by synovial inflammation, which can lead to deformation, bone erosion in addition to loss of joint function
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The inhibition of 3.7 nM TGR with 250 M inhibitor, 100 M NADPH, and a 15 min pre-incubation at RT was measured to compare to the inhibition after the jump dilution
