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In vivo endothelial cell-specific knockout of MET (through the generation of Tie-Cre Met fl/fl mice) led to normalised vasculature, reduced intra-tumoural hypoxia, slowed glioblastoma growth and importantly, sensitised glioblastoma tumours to temozolomide treatment, prolonging mouse survival [40]

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10.1016/j.jbc.2021.101096 6

"Shutting down Wnt signal-activated cancer"

Prioritize sleep (79 hours) to maximize natural recovery and repair mechanisms
