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In contrast, cysteine (Cys) and threonine (Thr) deprivation led to cell death via distinct pathways: ferroptosis for Cys starvation, whereas Thr deprivation triggered a previously uncharacterized form of cell death, which could be entirely suppressed by methionine (Met) co-starvation, and mTOR or translational inhibition

In Phase-I HSB, supplementation with 1% or 2% glycine increased ( P 0.05) in these variables between the 1% and 2% glycine groups

doi: 10.1016/j.jmb.2009.08.038
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6 Free Radical Biology & Medicine (PubMed)Glutathione in detoxification and as a cofactor for glutathione peroxidase and conjugation reactions
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