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Rubbing can push medication out of the subcutaneous layer and increase bruising
If nerves are involved or levels are critically low, injection is the smarter, faster choice
If your tirzepatide has been out of the fridge for extended periods , the expiration timeline may have shortened significantly
Refrain from touching the treated area for at least 4 hours post-treatment
doi:10.1124/jpet.114.217463 Parent MJ, et al
A 25 to 27 gauge needle is appropriate, as it minimizes discomfort and is sufficient for penetrating the subcutaneous layer without reaching the muscle
