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10.1073/pnas.0607260103 20 CoffmanC.HarrisW.KintnerC

Pancreatic polypeptide and its fragments: receptor interactions and biological activity

Imbalances in this system have been identified as a daily pathological basis for various diseases (176)

It has been studied in in vitro cell biology research examining telomerase activation, DNA methylation patterns, and cell cycle regulation

There are three known genes which encode this enzymatic activity in humans, ALDH1A1 , ALDH2 , and the more recently discovered ALDH1B1 (previously known as ALDH5 )

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