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( PMID: 14637183 )

Healthy mitochondria are essential for maintaining energy levels, cognitive function, and overall vitality as we age

ATPase assay Crude membrane protein (100 g protein/ml) from either High-five cells expressing ABCB1 or ABCG2 was incubated at 37C with varying concentrations of plumbagin and vitamin K3 in the presence and absence of BeFx (0.2 mM beryllium sulfate and 2.5 mM sodium fluoride) in ATPase assay buffer (50 mM KCl, 5 mM NaN 3 , 2 mM EGTA, 10 mM MgCl 2 , 1 mM DTT pH 6.8) for 10 min

TMX2 TMX2, which is localized in the MAM compartment, acts as an important sensor of redox conditions and is crucial for the maintenance of cellular redox homeostasis (Vandervore et al., 2019)

Additionally, thanks to its role in reducing free radicals, it can provide powerful anti-aging properties by helping reduce signs of aging

Topical niacinamide also inhibits the production of oil, which is a benefit to people dealing with acne