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Senescent cells upregulate FOXO4 expression to sequester p53 in the nucleus, preventing it from initiating the mitochondrial apoptosis pathway

Nukina N, Ihara Y (1986) One of the antigenic determinants of paired helical filaments is related to tau proteins

Answer at the end of the lesson

PMID: 21270715 Smith, H.E., Kerr, S.M., Fehlings, M.G., Chapman, J., Maltenfort, M., Zavlasky, J., Harris, E., Albert, T.J., Harrop, J., Hilibrand, A.S., Anderson, D.G., Vaccaro A.R..: Trends in Epidemiology and Management of Type II Odontoid Fractures: 20 year experience at a Model System Spine Injury Tertiary Referral Center

Adenosine - fights signs of aging, improves skin texture

A concentration of 50 mol/L artesunate selectively induces cell death in head and neck cancer cells without affecting normal cells by activating an iron-dependent, ROS-accumulating ferroptosis pathway [139]
