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Randomization was conducted using an interactive web response system, assigning participants in a 6:1 ratio to one of several treatment arms: once-weekly subcutaneous Cagrilintide administered in doses of 0.3, 0.6, 1.2, 2.4, or 4.5 mg, once-daily liraglutide 3.0 mg, or a volume-matched placebo

IC/BPS phenotypes exhibit different symptom presentations, including widespread phenotypes demonstrating increased sites of pain the body, fatigue, energy depletion, cognitive dysfunction, and emotional distress versus individuals with localized pain confined to the bladder or pelvic region only without the associated non-urologic symptoms

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This is particularly crucial given its potential impact on various cellular signaling pathways, which could pose serious risks

however, there is no long-term data