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Secondly, motivated by the need for a more relevant measure of destructive brain pathology, AVONEX clinical trial investigators pre-specified brain atrophy as an exploratory measure, and applied a new highly precise measure of brain atrophy, the so-called brain parenchymal fraction, to images collected during the trial

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It also influences the expression of various growth factors, such as growth hormone receptors, which are crucial for tissue repair and regeneration, he added