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By selectively disrupting key antioxidant systemssuch as inhibiting glutathione synthesis with buthionine sulfoximine (BSO), blocking thioredoxin reductase with auranofin, or directly targeting NRF2therapies can push cancer cells beyond their limited oxidative buffering capacity

Summary Glutathione is a potent antioxidant, and we need to maintain high antioxidant levels to fight oxidative stress from environmental toxins and aging

Medical Subject Headings

Bader, M

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