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As such, the IGF protein family continues to be a viable target for new therapeutic agents

Elevation of ROS levels results in oxidative stress in airway epithelial cells which activates an antioxidant defence mechanism known as the Keap1Nrf2 pathway to counteract the harmful effects of oxidative stress (Schieber and Chandel 2014)

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Antioxid Redox Signal 2004;6:81924