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Genetically encoded redox reporters (compartment-targeted) Target HyPer variants or roGFP-Orp1/roGFP2-Tsa2(C) to the matrix, IMS, outer membrane, ER lumen, peroxisomes, nucleus, or PM microdomains to resolve localized H 2 O 2 dynamics with minimal pooling (Malinouski et al

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Furthermore, cAMP and its downstream signaling pathways are known to regulate PCSK9 homeostasis and LOX-1 expression 45,46