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doi: 10.1136/bmj.l476

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Qu es la CTD

As stated above, according to several evidence, acute COVID-19 damage to the CNS may play a central role in the pathogenesis of neuropsychiatric symptoms through several pathophysiological mechanisms: dysregulation of inflammation, astrocytic glial damage, glutamatergic impairment (shift in tryptophan metabolism towards kynurenine pathway, Nf-B, oxidative stress, glutamatergic and excitotoxic damage) and possible glymphatic impairment [15, 46, 82]

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Overall, 60 of 60 genotypes matched for a concordance rate of 100%