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Although the tissue distribution of CD38 has been widely studied and described, its functions remain only partially understood

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It has no withdrawal syndrome and no rebound hyperglycemia in non-diabetic subjects

Peptide therapy can enhance insulin sensitivity, enabling the body to utilize glucose effectively

Whether their heterogeneity and different response levels to CD38 mAb in patients contribute to different outcomes following Daratumumab therapy requires more evidence (Figure 5) [55]

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