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The upregulated urea cycle removes -amyloid and ammonia on one hand, while on the other, overproduction of the urea cycle metabolite ornithine leads to the overexpression of the enzyme ornithine decarboxylase 1 (ODC1), which produces excessive putrescine that subsequently degrades into GABA, H 2 O 2 and ammonium (see previous section)

It boosts the innate immune response by encouraging the development of antimicrobial peptides like cathelicidins and defensins, which help fight respiratory infections

SBP: systolic blood pressure

doi: 10.2147/jir.S237049 113 BarraNGFanIYGillenJBChewMMarcinkoKSteinbergGRet al

4.4 Maternal RPM supplementation and offspring performance Considering that embryonic development is the period of extensive epigenetic reprogramming, maternal nutrition during the periconceptional and early pregnancy stages plays a crucial role in establishing the molecular and physiological foundations for fetal growth and long-term offspring performance

The residues were then resolved in 200 L 80% methanol for further HPLC analysis