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This type of pain can worsen with movement or sitting for long periods of time

Sahu B, Tikoo O, Pati B, Senapati U, Bal NC

doi: 10.1038/onc.2008.24

An update on neurobiological mechanisms involved in the development of chemotherapy-induced cognitive impairment (CICI)
& Swaan, P

McCully KS (1969) Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis