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During HBs specification, the pioneer factors recruit EZH2, a histone methyltransferase (KMTs) that catalyzes histone three lysine 27 (H3K27) me3, to silent pancreatic-specific genes in HBs (Tachmatzidi et al., 2021), which exerts unique functions in liver-specific gene activation by interacting and travelling with RNA polymerase II from the distal to proximal regions of transcription start sites (Horisawa et al., 2020)
Grace Morgan Jul 23rd, 2025 10/10 recommend
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