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In the development world, ARA-290 is very much a drug candidate: it has gone through formal preclinical programs and early-phase clinical trials in conditions like small fiber neuropathy, neuropathic pain, and sarcoidosis-related nerve damage

The effect of secukinumab on moderate-to-severe scalp psoriasis: results of a 24-week, randomized, double-blind, placebo-controlled phase 3b study

Proc Natl Acad Sci USA 115(15):37423744