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GS mRNA levels changed in parallel to that of GCLC in all three conditions while GCLM mRNA levels were unchanged [26,51,142]

L., Burger, H

Together, these findings suggest that circadian susceptibility in asthma may reflect impaired temporal coordination and intracellular competence of innate immune cells to execute melatonin-dependent redox buffering programs and identify the NRF2 glutathione axis as a therapeutically actionable pathway

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