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Disruption at any stage of this process can lead to damage in sperm quality

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X., et al., Nanomedicine Based on Natural Products: Improving Clinical Application Potential, Journal Of Nanomaterials 2022 (2022): 11

determined that ferroptosis is a key mechanism underlying blood-retinal barrier damage in diabetic retinopathy, demonstrating that Flotillin-1 activates the Nrf2 pathway by enhancing its expression and promoting its nuclear translocation, thereby stimulating the SLC7A11/GPX4 pathway to inhibit lipid peroxidation and ferroptosis [168]