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Description

Sp 1 is a bond, -S-, -0-, -CO H-, - HCO-, ~ R'~, -N(CH 2 CH 2 )2N-, or -X- Ar Y (CH 2 ) n Z wherein X, Y, and Z are independently a bond, ~NR'~, S , or O , with the proviso that when n=0, then at least one of Y and Z must be a bond and Ar' is 1,2-, 1,3-, or 1,4-phenylene optionally substituted with one, two, or three groups of (C 1 -C 5 ) alkyl, (C1-C4) alkoxy, (C1-C4) thioalkoxy, halogen, nitro, -COOR', --CONHR', -(CH 2 )nCOOR, - -S(CH 2 ) n COOR, -O(CH 2 ) n CONHR', or -S(CH 2 ) n CONHR, with the proviso that when Alk' is a bond, Spi is a bond

Bovine serum albumin insulin Glutathione-S-Transferase myoglobin

Whether there will be equal accessibility to gene therapy for individuals with SCD in the US or globally is a challenging question for healthcare providers to answer

Van den Bent MJ, Hegi ME, Stupp R

RNA sequencing libraries were prepared with unique barcodes using the NEBNext Ultra RNA library kit for Illumina (New England Biolabs) according to manufacturers instructions