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The cell releases its stored contents: histamine, tryptase, prostaglandins, leukotrienes, and a cocktail of other inflammatory mediators

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SAPK/JNK signaling pathway The stress-activated protein kinase/c-Jun N-terminal kinase pathway (SAPK/JNK) plays a crucial role in regulating cell growth, apoptosis, and inflammatory response [127, 128]

Esophagogastroduodenoscopy showed esophagitis and colonoscopy showed normal appearance of the mucosa

doi: 10.1038/ajg.2009.231

doi: 10.1016/j.ygcen.2004.12.018 5 HauserASAttwoodMMRask-AndersenMSchithHBGloriamDE
