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Description
Start with lower doses to assess tolerance, gradually increasing as appropriate
A more complex and potentially more useful experimental design allows the exploration of the relationship between efficacy and toxicity of immunoactivating biologics
Obesity also alters hormone levels by converting androgens into estrogens, leading to decreased testosterone
Chung, J.-S., Bonkobara, M., Tomihari, M., Cruz, P
Average fold inductions of AroB and ERa were increased relative to vehicle controls, but these differences were not statistically significant, likely due to a large variation in fold changes among biological replicates
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