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Kamisako et al., 2000
[DOI] [PMC free article] [PubMed] [Google Scholar] 164.Li Z, Wu N, Wang J, and Zhang Q

Interdependence between degree of porphyrin excess and disease severity in congenital erythropoietic porphyria (Gnthers disease)

when amounts of NAD+ are low in the body, the DDR process is impaired, resulting in increased damage to the cellular DNA

Genes (Basel) (2019) 10(2):105

In aged animals, folic acid deficiency exacerbates the pro-inflammatory microglia response in a model of ischemic brain injury [68], thereby contributing to increased neuronal damage under folate-deficient conditions
