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(5) suggested that the reduction of MDH2 has a negative impact on energy metabolism of spermatozoa, disrupting sperm motility, capacitation, and ultimately fertilizing ability

doi: 10.1093/hr/uhac196 95 TangM.ZhangH.WanY.DengZ.QinX.LiR.et al

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For the colorectal cancer PDX study, female NCR nude mice (CrTac:NCr- Foxn1 nu from Taconic) were implanted subcutaneously with low-passage KRAS-mutant CRM 13180 tumour fragments (30 mg) into the region of the right axilla