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It is well known that the epsilon four allele of the apolipoprotein E (APOE) gene located on chromosome 19 is a risk factor for the development of sporadic AD [22]

J., Lockwood, C., & Stout, J

Metabolic endpoint measurements Oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) are important parameters reflecting glycolysis levels

New imaging techniques, particularly confocal laser endomicroscopy, allow in vivo evaluation of the integrity of intestinal barrier after intravenous administration of fluorescein as a contrast agent

Samples were prepared in triplicate and were stored in the dark at 42 C with 25% relative humidity (RH) in an accelerated degradation chamber, as 2 weeks storage under these conditions is equivalent to approximately 6 weeks storage under ambient conditions [29, 30]

A series of 2D 1 H- 15 N HSQC spectra were collected at protein-to-ligand molar ratio of 1:0, 1:0.5, 1:1, 1:1.5, 1:2, 1:2.5, 1:3, 1:5, 1:7, 1:10, 1:15, 1:20, 1:30, 1:40, 1:50 and 1:60 for GlcNAc and 1:0, 1:0.5, 1:1, 1:1.5, 1:2, 1:2.5, 1:3, 1:4, 1:5, 1:6, 1:8, 1:10, 1:15 and 1:20 for GlcNAc1-2Man