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MOTS-c improves insulin sensitivity and glucose uptake

Brown fat burns energy for heat through a process called thermogenesis, and it is metabolically beneficial

The category Other for CV inclusion criteria includes patients where it is unknown if the patient fulfilled only one or several criteria and patients who were randomized in error and did not fulfill any criteria

Unlike most peptides, which are derived from nuclear DNA, MOTS-c originates from the mitochondria, underscoring its intimate connection to cellular energy processes

Conversely, proinflammatory Proteobacteria species have an elevated concentration in ME/CFS (191, 194)

An RCT by Maladkar et al