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Another study showed that Al reduced the A degradation by decreasing the activity of cathepsin B, suggesting the activation of the amyloidogenic pathway and a reduction of the catabolism of A (Sakamoto et al., 2006)

[226] Contact your healthcare provider or pharmacist if you are unsure about what to do regarding a missed dose

It also chelates metal ions, particularly copper and iron, which contribute to oxidative stress and A aggregation in AD

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Conclusions In Alzheimers disease (AD), ROS/RNS levels are accentuated, with a drop in the antioxidant response, leading to an environment conducive for the development of neuroinflammation and progression of the pathology

Gao, G., Shi, Y., Deng, H.-X