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Effective communication is a fundamental requirement for obtaining informed consent , which necessitates that patients fully understand their diagnosis, the proposed intervention, alternatives, and potential risks
Serrano-Villar S, Wu K, Hunt PW, Lok JJ, Ron R, Sainz T, et al
Matching treatment intensity to disease biology is critical to achieving a high therapeutic index which maximizes oncologic control and minimizes normal tissue toxicity
Traditional antifolate chemotherapeutics have many deleterious side effects due to the importance of folate pathways in healthy proliferating cells and Table 1: Established anti-folate antineoplastic agents (Newman A C and Maddocks O D K, 2017) One-carbon metabolism plays a significant role in References: Kalhan S C
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Microneedling is a collagen-stimulating treatment that may help improve skin texture, firmness, and the appearance of early lines
