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In most of those cases, there was a better path available

Proteins are typically sensitive to slight changes in solution chemistry
doi: 10.1111/pedi.12305
Dos Santos Tramontin N, da Silva S, Arruda R, Ugioni KS, Canteiro PB, de Bem Silveira G, Mendes C, Silveira PCL, Muller AP

Pharmaceutical companies, payers, and public health organizations are the most significant customers, using this data in drug development, clinical trials, and epidemiological models

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