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Members of the vascular endothelial growth factor (VEGF) family and anti-fibrotic bone morphogenetic protein (BMP) family members ( Bmp2 , Bmp4 , Bmp6 ) were significantly downregulated by approximately 63% to 73% in the HFD group

Although the STAR gene lacks a consensus binding site for canonical cAMP-activated transcription mediated by cAMP response element-binding protein (CREB) family member transcription factors, cAMP does indeed result in increased STAR transcription

The panel covers key steroid classes and pathway-associated metabolites, including estrogens, androgens, progestogens, glucocorticoids, mineralocorticoids, cholesterol, and other steroid hormone-related intermediates, enabling a more integrated view of steroid hormone biosynthesis