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Hydrogen, a novel antioxidant substance, can exert antioxidant effects by selectively neutralizing the most toxic reactive oxygen species, hydroxyl radicals, as well as mediated by a number of fine-tuned signaling pathways, such as the nuclear factor erythroid2-related factor 2 (NRF2) pathway

doi: 10.1523/jneurosci.6210-10.2011 142

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Also, baicalein is involved in the reduction of the phosphorylation of p65 and the nuclear translocation and downregulation of the DNA-binding activity of the NF-B in the STAT3 and cyclin D1 expression [73]