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The observation of widespread RCD in the brain of pre-clinical in vivo developmental models prompted further investigations to find the causative underlying pathways which precede the activation (Figure 6)

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There may be further interactions and side effects than listed

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In this study, we observed reduced FSP1 expression in the kidneys of oxalate-induced AKI mice and found that its deficiency promoted ferroptosis, thereby exacerbating renal injury