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Inadequate synthesis of carnitine produces carnitine depletion in dialysis patients, resulting in carnitine depletion and a simultaneous relative rise in esterified carnitine in certain individuals (Matera et al., 2003)

Walau bagaimanapun, terdapat beberapa kebimbangan mengenai kemungkinan kesan sampingannya, terutamanya pada dos yang lebih tinggi

Vermeulen RCW, Scholte HR

Simply consuming L-carnitine may not be enough to support increases in L-carnitine levels, there are different forms of L-carnitine available that are attached to different compounds that increase L-carnitine bioavailability and promote varying effects

Some of the main known factors are related to androgens

Carnitine can also reverse the harmful neuroinflammatory effects caused by activated microglia, which are resident immune effector cells in the central nervous system [104]