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[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Kuang R, OKeefe SJD, Ramos Del Aguila de Rivers C, Koutroumpakis F, Binion DG

doi: 10.3748/wjg.14.6145
(2023) in The Lancet showed clinically meaningful HbA1c and body-weight reductions versus dulaglutide in the active-comparator arm
C.ChenY.et al (2018)

As a result, I view Epithalon as a promising investigational therapy rather than a proven longevity intervention

As PLP is as a required cofactor of aminotransferases, decreased availability of PLP due to TNSALP deficiency impairs the normal function of these enzymes
