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Notably, for SnCE1 C256A we observed slight remaining activity after 60 min suggesting that Ser208 can replace Cys256 as nucleophile to some extent, however, only in the context of the mutation C256A (Fig

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Neuropharmacology 67:243251

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K.MishraA.JhaB

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Hydroxylation of lysine residues is the first modification catalyzed by lysyl hydroxylases, and is critical for the following glycosylation and in determining the fate of covalent cross-linking

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