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The overproduction of inflammatory mediators (such as TNF-, IL-1 and NO) by microglial cells is involved in the neurodegenerative AD and Parkinsons disease (PD), as they can damage neurons (Smith et al., 2012
Table 7 mentions several studies conducted in this field
One significant impact of ROS is lipid peroxidation, a process triggered when membrane phospholipids encounter an ROS oxidizing agent (Yadav et al., 2019)
Nat Rev Endocrinol 13(10):610622 Kujur A, Srivastava N, Kumar B, Jasrotia N, Arunpandian J, Ganeshan M (2021) Fetal congenital goiter in goat: a case report
W., Hanczko R., Bonilla E., Caza T
CASTOR1/2, another GATOR2-binding protein in arginine-depleted conditions, has been validated as a cytosolic arginine sensor (Chantranupong et al., 2017)
