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Liu and collaborators conjugated poly(-lipoic) nanoparticles to combretastatin A4, a potent vascular disrupting agent, resulting in a specific accumulation of combretastatin A4 in tumour cells and in a prolonged apoptosis of cancer cells because of its long retention time [185]

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Giuliani V,Jiang Y,Johnson SB,Johnson TA,Kang Z,Leonard PG,Liu Z,McAfoos T,Miller M,Morlacchi P,Mullinax RA,Palmer WS,Pang J,Rogers N,Rudin CM,Shepard HE,Spencer ND,Theroff J,Wu Q,Xu A,Yau JA,Draetta G,Toniatti C,Heffernan TP,Jones P

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