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[DOI] [PMC free article] [PubMed] [Google Scholar] 148.Prasad C, Imamura M, Debata C, Svec F, Sumar N, Hermon-Taylor J

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The cytosolic AST enzyme is encoded by the glutamate oxaloacetic transaminase 1 gene (GOT1)

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Experimental evidence shows that alcohol consumption does indeed result in significant hypoxia in perivenous hepatocytes (hepatocytes that are located close to the vein where the cleansed blood exits the liver)

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In mice with diet-induced obesity, deletion of Arg1 or Arg2 gene or inhibition of arginase activity with ABH prevented vascular dysfunction [230, 231]

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In addition, high- M r -lyases occur in both cytosolic and mitochondrial fractions of the rat kidney and, to a lesser extent, rat liver

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